MCS Scientific LLC (formerly MCS Consulting) has supplied software for research in pharmacology since 1979. Our software, PHARM/PCS™ (based on the book Manual of Pharmacologic Calculations with Computer Programs, 2nd Edition by Ronald J. Tallarida and Rodney B. Murray, published by Springer-Verlag), is used at almost 400 sites worldwide, in both academic pharmacology and commercial pharmaceutical research labs.
Whether you teach pharmacology, conduct basic research, or administer clinical drug trials, MCS Scientific offers PHARM/PCS to make you and your staff more productive. Please take some time to review the following pages. If you have any questions, do not hesitate to contact us. Pharm/PCS includes these 48 procedures:
1. Dosage and Concentration: Drug Stock Solutions
2. Mean, Standard Deviation and Confidence Limits
3. Linear Regression I
4. Linear Regression II: Lines Through Origin
5. Analysis of the Regression Line
6. Parallel Lines I: Test for Parallelism
7. Parallel Lines II: Construction of Parallel Lines
8. Graded Dose-Response
9. Quantal Dose-Response: Probits
10. Relative Potency I
11. Relative Potency II: Statistical Analysis
12. Dissociation Constant I: Agonists
13. Dissociation Constant II: Partial Agonists
14. Dissociation Constant III: Perturbation Methods
15. pA2 Analysis I: Schild Plot
16. pA2 Analysis II: Time-Dependent Method
17. pA2 Analysis III: Constrained Plot
18. Enzyme Kinetics I: Michaelis-Menten Equation
19. Enzyme Kinetics II: Competitive Inhibition
20. Enzyme Kinetics III: Noncompetitive Inhibition
21. First Order Drug Decay
22. Scatchard Plot
23. Henderson-Hasselbalch Equation
24. Exponential Growth and Decay
25. Area Under a Curve: Trapezoidal and Simpson's Rules
26. Pharmacokinetics I: Constant Infusion, 1st Order Elimination
27. Pharmacokinetics II: Multiple IV Injections
28. Pharmacokinetics III: Volume of Distribution
29. Pharmacokinetics IV: Plasma Concentration-time Data
30. Pharmacokinetics V: Renal Clearance
31. Pharmacokinetics VI: Renal Excretion Data Following IV Administration
32. Pharmacokinetics VII: Multiple Dosing from Absorptive Site
33. Analysis of Variance I: 1-Way
34. Analysis of Variance II: 2-Way, Single Observation
35. Analysis of Variance III: 2-Way, with Replication
36. Newman-Keuls Test
37. Duncan Multiple Range Test
38. Least Significant Difference Test
39. t-Test I: Grouped Data
40. t-Test II: Paired Data
41. Ratio of Means
42. Chi-Square Test
43. Proportions: Confidence Limits
44. Dunnett's Test (Comparison with a Control)
45. Mann-Whitney U-Test
46. Litchfield and Wilcoxin I: Confidence Limits of ED5O
47. Litchfield and Wilcoxin II
48. Differential Equations
Learn more about the authors:
Whether you teach pharmacology, conduct basic research, or administer clinical drug trials, MCS Scientific offers PHARM/PCS to make you and your staff more productive. Please take some time to review the following pages. If you have any questions, do not hesitate to contact us. Pharm/PCS includes these 48 procedures:
1. Dosage and Concentration: Drug Stock Solutions
2. Mean, Standard Deviation and Confidence Limits
3. Linear Regression I
4. Linear Regression II: Lines Through Origin
5. Analysis of the Regression Line
6. Parallel Lines I: Test for Parallelism
7. Parallel Lines II: Construction of Parallel Lines
8. Graded Dose-Response
9. Quantal Dose-Response: Probits
10. Relative Potency I
11. Relative Potency II: Statistical Analysis
12. Dissociation Constant I: Agonists
13. Dissociation Constant II: Partial Agonists
14. Dissociation Constant III: Perturbation Methods
15. pA2 Analysis I: Schild Plot
16. pA2 Analysis II: Time-Dependent Method
17. pA2 Analysis III: Constrained Plot
18. Enzyme Kinetics I: Michaelis-Menten Equation
19. Enzyme Kinetics II: Competitive Inhibition
20. Enzyme Kinetics III: Noncompetitive Inhibition
21. First Order Drug Decay
22. Scatchard Plot
23. Henderson-Hasselbalch Equation
24. Exponential Growth and Decay
25. Area Under a Curve: Trapezoidal and Simpson's Rules
26. Pharmacokinetics I: Constant Infusion, 1st Order Elimination
27. Pharmacokinetics II: Multiple IV Injections
28. Pharmacokinetics III: Volume of Distribution
29. Pharmacokinetics IV: Plasma Concentration-time Data
30. Pharmacokinetics V: Renal Clearance
31. Pharmacokinetics VI: Renal Excretion Data Following IV Administration
32. Pharmacokinetics VII: Multiple Dosing from Absorptive Site
33. Analysis of Variance I: 1-Way
34. Analysis of Variance II: 2-Way, Single Observation
35. Analysis of Variance III: 2-Way, with Replication
36. Newman-Keuls Test
37. Duncan Multiple Range Test
38. Least Significant Difference Test
39. t-Test I: Grouped Data
40. t-Test II: Paired Data
41. Ratio of Means
42. Chi-Square Test
43. Proportions: Confidence Limits
44. Dunnett's Test (Comparison with a Control)
45. Mann-Whitney U-Test
46. Litchfield and Wilcoxin I: Confidence Limits of ED5O
47. Litchfield and Wilcoxin II
48. Differential Equations
Learn more about the authors: